HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Benzylnormechlorethamine → 1-Benzyl-4-[4-(3-methyl-butoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Benzylnormechlorethamine | HCID 5928 | — |
| Reactant | [4-(3-Methyl-butoxy)phenylsulfonyl]-acetic acid ethyl ester | HCID 11088330 | — |
| Product | 1-Benzyl-4-[4-(3-methyl-butoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid ethyl ester | HCID 10906839 | — |
Reaction Steps
1-Benzyl-4-[4-(3-methyl-butoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid ethyl ester was prepared according to the general method outlined in example 83 starting from [4-(3-methyl-butoxy)-phenylsulfonyl]-acetic acid ethyl ester (6.2 g, 20 mnmol) and bis-(2-chloro-ethyl)-benzyl amine (6.44 g, 24 mmol). Yield 8 g (84%); yellow oil; MS: 474 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06441023B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-10edf2cc9d6146e8aa0ac12864463de6 |
| Source note | uspto-grants-2002_08 |