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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2306060Generated: November 2, 2026

Ethanol → Ethyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoate

https://huagongshe.com/reaction/2306060

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant2-(4-Cyclopropanecarbonyl-phenyl)-2-methylpropionamideHCID 23499851—
ProductEthyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoateHCID 9813859—

Reaction Steps

Dissolve 2-(4-cyclopropanecarbonyl-phenyl)-2-methyl-propionamide (100 mg) in ethanol and bubble in hydrochloride gas for 5 minutes while stirring. Reflux for 10 hours, distill off the ethanol and extract into ethyl acetate. Evaporate the solvent in vacuo to give the little compound as an oil (50 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06441179B1
Source datasetuspto-grants-2002_08
ORD IDord-55b635903a624a3294da0b7f89b39e81
Source noteuspto-grants-2002_08