HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylhydantoin → HCID 178491128, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylhydantoin | HCID 6491 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Diisopropyl diazene-1,2-dicarboxylate | HCID 75555 | — |
| Reactant | HCID 178491130 | HCID 178491130 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178491128 | HCID 178491128 | — |
Reaction Steps
A solution of Example 1H (2.80 kg), triphenylphosphine (2.475 kg), and 5,5-dimethylhydantoin (1.37 kg) in THF (24.89 kg) at 1-2° C. was treated with diisopropyl azodicarboxylate (2.01 kg) over 75 minutes to provide a solution of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06441189B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-95e3e9088bb14684a74fde423c766a2d |
| Source note | uspto-grants-2002_08 |