Water → (1E)-1-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-1,2-propanedione 1-(O-methyloxime)

Participants

Reaction Steps

20 g (0.14 mol) of pentane-2,3,4-trione 3-(O-methyloxime), 43.4 g (0.42 mol) of neopentyl glycol and 0.1 g of conc. sulfuric acid in 80 ml of toluene were heated at the boil on a water separator at a pressure of 800 mbar for 2 hours. The mixture was extracted with water and toluene and then worked up as in Example 4b). This gave 30 g of an oil of a purity of 84% (yield 79%).

Provenance & Evidence