Boc-L-methionine → (S)-1-(3-Bromo-7-tert-butoxynaphthalen-1-yl)-3-(tert-butoxycarbonylamino)-2-oxopyrrolidine

Participants

Role	Name	HCID	Charge
Reactant	Boc-L-methionine	HCID 89857	—
Reactant	(3-(Benzyloxy)phenyl)methanamine	HCID 11009288	—
Reactant	1-Amino-3-bromo-7-tert-butoxynaphthalene	HCID 18433586	—
Product	(S)-1-(3-Bromo-7-tert-butoxynaphthalen-1-yl)-3-(tert-butoxycarbonylamino)-2-oxopyrrolidine	HCID 70171503	—

Reaction Steps

Following the procedures described in Example 1, Steps J-L, but using 1-amino-3-bromo-7-tert-butoxynaphthalene, as described in Example 46, Step H, in place of 3-benzyloxybenzylamine, and (S)-N-(tert-butoxycarbonyl)methionine in place of (R)-N-(tert-butoxycarbonyl)methionine in Step J, the above-titled compound was obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06441017B1
Source dataset	uspto-grants-2002_08
ORD ID	ord-890e69a45e1a44e7bd0757e501fb6c43
Source note	uspto-grants-2002_08