Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Triisopropylsilyl chloride | HCID 139400 | — |
| Reactant | 8-Iodo-2-naphthol | HCID 622986 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18536138 | HCID 18536138 | — |
Reaction Steps
1-Iodo-7-hydroxynaphthalene, as described in Step A, (15.84 g, 58.65 mmol), imidazole (5.59 g, 82.11 mmol) and triisopropylsilyl chloride (17.6 mL, 82.11 mmol) were dissolved in DMF (40 mL) and heated to 40° C. for 18 hours. The reaction was poured into H2O and extracted with hexanes (3×). The combined organic extracts were dried over Na2SO4, filtered and concentrated in vacuo, to yield the above-titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06441017B1 |
|---|
| Source dataset | uspto-grants-2002_08 |
|---|
| ORD ID | ord-0f5c65a087634931a8d9339496584041 |
|---|
| Source note | uspto-grants-2002_08 |
|---|
