Acetyl chloride → 1-Acetyl-2-(4-bromophenyl)pyrrolidine

HRID 230638Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)=[CH:4][CH:3]=1.[C:13](Cl)(=[O:15])[CH3:14]>>[C:13]([N:9]1[CH2:10][CH2:11][CH2:12][CH:8]1[C:5]1[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=1)(=[O:15])[CH3:14]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 42814942-(4-Bromophenyl)pyrrolidine

Product 1

HCID 577628221-Acetyl-2-(4-bromophenyl)pyrrolidine

Procedure

The title compound was prepared from 2-(4-bromophenyl)pyrrolidine and acetyl chloride using a similar procedure to that described in description 25.

Sources & evidence

ORD record: ord-ed14abbda5904a78bfa0dafec6a5f394
Source dataset: uspto-grants-2009_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07566735B2

Reaction notes

Loading…