HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → HCID 18434283, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | N-Methylallylamine | HCID 69391 | — |
| Reactant | 2,4-Difluorobenzoyl chloride | HCID 588081 | — |
| Reactant | trans-1,4-Dibromo-2-butene | HCID 641245 | — |
| Reactant | 2,5-Difluoroanisole | HCID 2724989 | — |
| Reactant | HCID 18434165 | HCID 18434165 | — |
| Product | HCID 18434283 | HCID 18434283 | — |
Reaction Steps
from 2,4-difluorobenzoyl chloride and 2,5-difluoroanisole via (2,4-difluoro-phenyl)-(2,5-difluoro-4-methoxy-phenyl)-methanone, which is deprotected with hydrogen bromide and reacted with (E)-1,4-dibromo-2-butene and N-allyl-methyl-amine, there is obtained (E)-[4-[4-(allyl-methyl-amino)-but-2-enyloxy]-2,5-difluoro-phenyl]-(2,4-difluoro-phenyl)-methanone•hydrochloride (1:1), m.p. 141° C.,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06441177B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-5d6879e0c94c4b67881a031819b436a8 |
| Source note | uspto-grants-2002_08 |