HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → 1-(3,5-dinitrobenzyl)-2,3,3-trimethyl-3H-indolium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 3H-Indole, 2,3,3-trimethyl- | HCID 15427 | — |
| Reactant | Benzene, 1-(chloromethyl)-3,5-dinitro- | HCID 94673 | — |
| Solvent | Sulfolane | HCID 31347 | — |
| Product | 1-(3,5-dinitrobenzyl)-2,3,3-trimethyl-3H-indolium iodide | HCID 17902140 | 57% |
Reaction Steps
3,5-Dinitrobenzyl chloride (100 mg, 0.46 mmol), 2,3,3-trimethylindole (74 μ, 73.2 mg, 0.46 mmol) and sodium iodide (69 mg, 0.46 mmol) were heated at 100° C. in sulpholane (5 ml) for 16 hours. After cooling to room temperature the product was isolated by reverse phase HPLC (89.7 mg, 0.26 mmol, 57% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06828116B1 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-0dd40617dc424c7cac1f85de59099d2b |
| Source note | uspto-grants-2004_12 |