1,3-Cyclohexanedione → HCID 69916322, compound

Participants

Reaction Steps

0.550 g (1.60 mmol) of 2-chloro-3-cyclopentylmethoxy-4-ethylsulfonylbenzoic acid, 0.196 g (1.70 mmol) of cyclohexane-1,3-dione, 0.279 g (1.40 mmol) of N′-(3-dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride and 0.002 g of dimethylaminopyridine were stirred for 10 hours at room temperature in 15 ml of methylene chloride. The mixture was subsequently diluted with methylene chloride and washed with 0.5 N HCl, with water, with saturated NaHCO3 solution and again with water. After the combined organic phases had been dried over Na2SO4 and evaporated completely on a rotary evaporator, 3-oxo-1-cyclohexenyl 2-chloro-3-cyclopentylmethoxy-4-ethylsulfonylbenzoate was obtained in the form of a brown resin.

Provenance & Evidence