1-Bromo-4-(methylsulphonyl)benzene → HCID 24826949, compound

HRID 230658Notes

Reaction equation

HRID 230658 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8](Br)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[F:12][C:13]([F:24])([F:23])[C:14]1[C:22]2[CH2:21][CH2:20][CH2:19][CH2:18][C:17]=2[NH:16][N:15]=1>>[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([N:16]2[C:17]3[CH2:18][CH2:19][CH2:20][CH2:21][C:22]=3[C:14]([C:13]([F:12])([F:24])[F:23])=[N:15]2)=[CH:7][CH:6]=1)(=[O:4])=[O:3]

Participants

3

Reactant 2

HCID 770141-Bromo-4-(methylsulphonyl)benzeneHCID 28028633-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole

Product 1

HCID 24826949HCID 24826949, compound

Procedure

The title compound was prepared from 4-bromophenyl methyl sulfone and 3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole using a similar procedure to that described for Example 7.

Sources & evidence

ORD record
ord-89efa79804bf4ff7906a9b40d6ea6dd7
Source dataset
uspto-grants-2009_07
Patent number
US07566735B2

Reaction notes

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