6-Nitro-2-(phenylmethyl)-1H-benzimidazole → HCID 178507350, compound

HRID 2306673Notes

Reaction equation

HRID 2306673 reaction equation
[N+:1]([C:4]1[CH:19]=[CH:18][C:7]2[N:8]=[C:9]([CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[NH:10][C:6]=2[CH:5]=1)([O-])=O.NC1C=C2C(=CC=1)N(CC1C=CC=CC=1)C=C2>>[NH2:1][C:4]1[CH:19]=[CH:18][C:7]2[NH:8][C:9]([CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[N:10][C:6]=2[CH:5]=1

Participants

3

Reactant 2

HCID 235786-Nitro-2-(phenylmethyl)-1H-benzimidazoleHCID 27946241-Benzyl-1H-indol-5-ylamine

Product 1

HCID 178507350HCID 178507350, compound

Procedure

The title compound was prepared from 5-nitro-2-benzylbenzimidazole by an analogous reduction method to that described above for 5-amino-1-benzyl-1H-indole; m/z (M+1)+ 224. Also note the published method (J. Het. Chem., 23, 1109-13, (1986)).

Sources & evidence

ORD record
ord-21ea22d992b744178376b15fc77c2e43
Source dataset
uspto-grants-2004_12
Patent number
US06828320B2

Reaction notes

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