HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 178514413, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Bis-(1H-imidazol-2-YL)-methanone | HCID 5250894 | — |
| Reactant | HCID 178524140 | HCID 178524140 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178514413 | HCID 178514413 | — |
Reaction Steps
(4-Hydroxy-quinazolin-7-yl)-carboxylic acid (0.5 g) in dry THF (20 ml) was treated with carbonyl diimidazole (0.85 g) under nitrogen for 6 hours at room temperature. Hydrazine hydrate was added and stirring was continued for 18 hours. The mixture was filtered to give the title compound (0.41 g); m/z (M+1+) 205.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06828320B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-00e18b09f79541b3ba1a2ba958758f69 |
| Source note | uspto-grants-2004_12 |