Piperidine → 1-{4-[2-oxo-2-(1-piperidinyl)ethyl]phenyl}-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole

Participants

Role	Name	HCID	Charge
Reactant	Piperidine	HCID 8082	—
Reactant	{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}acetic acid	HCID 50992931	—
Product	1-{4-[2-oxo-2-(1-piperidinyl)ethyl]phenyl}-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole	HCID 24827143	—

Reaction Steps

The title compound was prepared from {4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}acetic acid and piperidine using a similar procedure to that described for Example 2, product further purified by mass directed auto-prep.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07566735B2
Source dataset	uspto-grants-2009_07
ORD ID	ord-482b5b32356748e59acdb37542f299c9
Source note	uspto-grants-2009_07