1-(3-Fluorobenzyl)-1H-indazol-5-amine → HCID 22609802, compound

HRID 2306722Notes

Reaction equation

HRID 2306722 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=1)[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([NH2:15])=[CH:12][CH:13]=2)[CH:8]=[N:7]1.[Cl:19][C:20]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([C:30]3[O:31][C:32]([CH3:35])=[N:33][N:34]=3)[CH:28]=2)[N:23]=[CH:22][N:21]=1>>[ClH:19].[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=1)[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([NH:15][C:20]3[C:29]4[C:24](=[CH:25][CH:26]=[C:27]([C:30]5[O:31][C:32]([CH3:35])=[N:33][N:34]=5)[CH:28]=4)[N:23]=[CH:22][N:21]=3)=[CH:12][CH:13]=2)[CH:8]=[N:7]1

Participants

3

Reactant 2

HCID 71470731-(3-Fluorobenzyl)-1H-indazol-5-amineHCID 226097254-Chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazoline

Product 1

HCID 22609802HCID 22609802, compound

Procedure

The title compound was prepared according to Procedure A from 1-(3-fluorobenzyl)-1H-indazol-5-ylamine and 4-chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)-quinazoline; δH [2H6]DMSO 11.80(1H, s), 9.45(1H, s), 8.90(1H, s), 8.60(1H, d), 8.25(1H, s), 8.13(2H, m), 7.87(1H, d), 7.79(1H, d), 7.39(1H, dd), 7.10(3H, m), 5.75(2H, s), 2.65 (3H, s); m/z (M+1+) 452.

Sources & evidence

ORD record
ord-203b2b56bfe74e64ad14021860a649e8
Source dataset
uspto-grants-2004_12
Patent number
US06828320B2

Reaction notes

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