N-Methylpropylamine → HCID 24825806, compound

HRID 230673Notes

Reaction equation

HRID 230673 reaction equation
[F:1][C:2]([F:23])([F:22])[C:3]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[N:5]([C:12]2[CH:17]=[CH:16][C:15]([CH2:18][C:19]([OH:21])=O)=[CH:14][CH:13]=2)[N:4]=1.[CH3:24][NH:25][CH2:26][CH2:27][CH3:28]>>[CH3:24][N:25]([CH2:26][CH2:27][CH3:28])[C:19](=[O:21])[CH2:18][C:15]1[CH:16]=[CH:17][C:12]([N:5]2[C:6]3[CH2:7][CH2:8][CH2:9][CH2:10][C:11]=3[C:3]([C:2]([F:1])([F:23])[F:22])=[N:4]2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 12315N-MethylpropylamineHCID 50992931{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}acetic acid

Product 1

HCID 24825806HCID 24825806, compound

Procedure

The title compound was prepared from {4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}acetic acid and N-methylpropylamine using a similar procedure to that described for Example 2, product further purified by mass directed auto-prep.

Workup

  1. customfurther purified by mass

Sources & evidence

ORD record
ord-e0c68f87719a4d1c9b0b994146f8e46b
Source dataset
uspto-grants-2009_07
Patent number
US07566735B2

Reaction notes

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