1-(Phenylmethyl)-1H-indazol-5-amine → HCID 22609833, compound

HRID 2306733Notes

Reaction equation

HRID 2306733 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([NH2:17])=[CH:14][CH:15]=2)[CH:10]=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:18][C:19]1[C:28]2[C:23](=[CH:24][CH:25]=[C:26]([C:29]3[O:30][C:31]([C:34]([F:37])([F:36])[F:35])=[N:32][N:33]=3)[CH:27]=2)[N:22]=[CH:21][N:20]=1>>[ClH:18].[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([NH:17][C:19]3[C:28]4[C:23](=[CH:24][CH:25]=[C:26]([C:29]5[O:30][C:31]([C:34]([F:37])([F:35])[F:36])=[N:32][N:33]=5)[CH:27]=4)[N:22]=[CH:21][N:20]=3)=[CH:14][CH:15]=2)[CH:10]=[N:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 2120691-(Phenylmethyl)-1H-indazol-5-amineHCID 226097564-Chloro-6-(5-trifluoromethyl-1,3,4-oxadiazol-2-yl)quinazoline

Product 1

HCID 22609833HCID 22609833, compound

Procedure

The title compound was prepared according to Procedure A from 1-benzyl-1H-indazol-5-ylamine and 4-chloro-6-(5-trifluoromethyl-1,3,4-oxadiazol-2-yl)-quinazoline; δ[2H6]DMSO 11.96(1H, bs), 9.58(1H, s), 8.91(1H, s), 8.69(1H, dd), 8.22(1H, s), 8.14(1H, d), 8.10(1H, d), 8.85(1H, d), 8.67(1H, dd), 7.30(5H, m), 5.71(2H, s); m/z (M+1+) 488.

Sources & evidence

ORD record
ord-ee7c233a2531409fbd4524ce89f9e4f5
Source dataset
uspto-grants-2004_12
Patent number
US06828320B2

Reaction notes

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