2-(Tributylstannyl)furan → HCID 22609804, compound

HRID 2306750Notes

Reaction equation

HRID 2306750 reaction equation
[ClH:1].[CH2:2]([N:9]1[C:17]2[C:12](=[CH:13][C:14]([NH:18][C:19]3[C:28]4[C:23](=[CH:24][C:25](I)=[CH:26][CH:27]=4)[N:22]=[CH:21][N:20]=3)=[CH:15][CH:16]=2)[CH:11]=[N:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[O:30]1[CH:34]=[CH:33][CH:32]=[C:31]1[Sn](CCCC)(CCCC)CCCC>>[ClH:1].[CH2:2]([N:9]1[C:17]2[C:12](=[CH:13][C:14]([NH:18][C:19]3[C:28]4[C:23](=[CH:24][C:25]([C:31]5[O:30][CH:34]=[CH:33][CH:32]=5)=[CH:26][CH:27]=4)[N:22]=[CH:21][N:20]=3)=[CH:15][CH:16]=2)[CH:11]=[N:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 43936882-(Tributylstannyl)furanHCID 219521701-benzyl-1H-indazol-5-yl(7-iodoquinazolin-4-yl)-amine hydrochloride

Product 1

HCID 22609804HCID 22609804, compound

Procedure

Prepared according to Procedure B from (1-benzyl-1H-indazol-5-yl)-(7-iodoquinazolin-4-yl)-amine hydrochloride and (furan-2-yl)-tri-n-butylstannane; δH [2H6]DMSO 9.94(1H, bs), 8.61 (1H, d), 8.55(1H, s), 8.21 (2H, d), 8.00(3H, m), 7.73(2H, s), 7.30(6H, s), 6.74(1H, s), 5.72(2H, s); m/z (M+1+) 418.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f4b5be67d10b4fe5aadb79dcc5ddf5f3
Source dataset
uspto-grants-2004_12
Patent number
US06828320B2

Reaction notes

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