3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole → HCID 24825811, compound

HRID 230677Notes

Reaction equation

HRID 230677 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:9]([CH3:13])[C:10](=[O:12])[CH3:11])=[CH:4][CH:3]=1.[F:14][C:15]([F:26])([F:25])[C:16]1[C:24]2[CH2:23][CH2:22][CH2:21][CH2:20][C:19]=2[NH:18][N:17]=1>>[CH3:13][N:9]([CH2:8][C:5]1[CH:6]=[CH:7][C:2]([N:18]2[C:19]3[CH2:20][CH2:21][CH2:22][CH2:23][C:24]=3[C:16]([C:15]([F:14])([F:26])[F:25])=[N:17]2)=[CH:3][CH:4]=1)[C:10](=[O:12])[CH3:11]

Participants

3

Reactant 2

HCID 28028633-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazoleHCID 12839032HCID 12839032, compound

Product 1

HCID 24825811HCID 24825811, compound

Procedure

The title compound was prepared from N-[(4-bromophenyl)methyl]-N-methylacetamide and 3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole using a similar procedure to that described for Example 1.

Sources & evidence

ORD record
ord-e6c883241168434a8721b67b873e899f
Source dataset
uspto-grants-2009_07
Patent number
US07566735B2

Reaction notes

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