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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 230678Generated: October 31, 2026

3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole → 1-({4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}methyl)-2-pyrrolidinone

https://huagongshe.com/reaction/230678

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazoleHCID 2802863—
Reactant1-(4-Iodobenzyl)pyrrolidin-2-oneHCID 50992862—
Product1-({4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}methyl)-2-pyrrolidinoneHCID 24825905—

Reaction Steps

The title compound was prepared from 1-[(4-iodophenyl)methyl]-2-pyrrolidinone and 3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole using a similar procedure to that described for Example 19.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07566735B2
Source datasetuspto-grants-2009_07
ORD IDord-0f4db5c7b6874c09b0637465f3024534
Source noteuspto-grants-2009_07