5-Methoxyindan-1-one → 2-(6-methoxy-1H-inden-3-yl)propanoic Acid

HRID 2306822Notes

Reaction equation

HRID 2306822 reaction equation
[O:1]([C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[C:8](=O)[CH2:7][CH2:6]2)[CH3:2].Br[CH:14]([CH3:19])[C:15]([O:17]C)=[O:16]>>[CH3:2][O:1][C:3]1[CH:4]=[C:5]2[C:9]([C:8]([CH:14]([CH3:19])[C:15]([OH:17])=[O:16])=[CH:7][CH2:6]2)=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 787875-Methoxyindan-1-oneHCID 95576Methyl 2-bromopropionate

Product 1

HCID 219427692-(6-methoxy-1H-inden-3-yl)propanoic Acid

Procedure

This substrate was prepared using the same procedures as described for Examples 1 and 2a, starting with 5-methoxyl-1-indanone and methyl 2-bromopropionate.

Workup

  1. customThis substrate was prepared

Sources & evidence

ORD record
ord-a1375343248f431da425995a9c50eefb
Source dataset
uspto-grants-2004_12
Patent number
US06828335B2

Reaction notes

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