Benzenepropanoic acid, 4-hydroxy-, methyl ester → HCID 22610298, compound

HRID 2306852Notes

Reaction equation

HRID 2306852 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12]C)=[O:11])=[CH:4][CH:3]=1.[CH:14]([C:27]1[C:35]2[C:30](=[CH:31][CH:32]=[C:33]([Cl:36])[CH:34]=2)[N:29]([CH2:37][CH2:38]O)[C:28]=1[CH3:40])([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH:14]([C:27]1[C:35]2[C:30](=[CH:31][CH:32]=[C:33]([Cl:36])[CH:34]=2)[N:29]([CH2:37][CH2:38][O:1][C:2]2[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])=[CH:6][CH:7]=2)[C:28]=1[CH3:40])([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 79706Benzenepropanoic acid, 4-hydroxy-, methyl esterHCID 22610292HCID 22610292, compound

Product 1

HCID 22610298HCID 22610298, compound

Procedure

The methyl ester of the title compound was prepared from methyl 3-(4-hydroxyphenyl)propionate and 2-(3-benzhydryl-5-chloro-2-methyl-1H-indol-1-yl)ethanol according to Step 2 of the procedures for Example 2.

Sources & evidence

ORD record
ord-1788b118980a4b15933f541266104ce0
Source dataset
uspto-grants-2004_12
Patent number
US06828344B1

Reaction notes

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