1-(Diphenylmethyl)azetidin-3-one → 3-(4-(Trifluoromethyl)phenyl)-1-(diphenylmethyl)azetidin-3-ol

HRID 2307229Notes

Reaction equation

[C:1]1([CH:7]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:8]2[CH2:11][C:10](=[O:12])[CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:19][C:20]([F:30])([F:29])[C:21]1[CH:26]=[CH:25][C:24]([Mg]Br)=[CH:23][CH:22]=1.ClC1C=CC(C2(O)CN(C(C3C=CC=CC=3)C3C=CC=CC=3)C2)=CC=1>>[F:19][C:20]([F:30])([F:29])[C:21]1[CH:26]=[CH:25][C:24]([C:10]2([OH:12])[CH2:11][N:8]([CH:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:9]2)=[CH:23][CH:22]=1