3-Chloro-3-(3-(trifluoromethyl)phenyl)-(diphenylmethyl)azetidine → 3-(3-(Trifluoromethyl)phenyl)-1-(diphenylmethyl)azetidine

HRID 2307234Notes

Reaction equation

HRID 2307234 reaction equation
Cl[C:2]1([C:19]2[CH:24]=[CH:23][CH:22]=[C:21]([C:25]([F:28])([F:27])[F:26])[CH:20]=2)[CH2:5][N:4]([CH:6]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:3]1.C(C1C=CC(C2CCN2C(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1)(C)(C)C>>[F:28][C:25]([F:26])([F:27])[C:21]1[CH:20]=[C:19]([CH:2]2[CH2:3][N:4]([CH:6]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)[CH2:5]2)[CH:24]=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 226054123-Chloro-3-(3-(trifluoromethyl)phenyl)-(diphenylmethyl)azetidineHCID 867595734-tert-Butylphenyl-1-(diphenylmethyl)azetidine

Product 1

HCID 226053953-(3-(Trifluoromethyl)phenyl)-1-(diphenylmethyl)azetidine

Procedure

This compound was prepared compound (37) using the procedure described for compound (11).

Sources & evidence

ORD record
ord-d1202ea486c548c1b7d94746b735fc76
Source dataset
uspto-grants-2004_12
Patent number
US06831078B1

Reaction notes

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