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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2307236Generated: November 1, 2026

Propargylamine → 3-(3-(Trifluoromethyl)phenyl)-N-(2-propynyl)azetidine-1-carboxamide

https://huagongshe.com/reaction/2307236

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropargylamineHCID 239041—
Reactant3-(3-(Trifluoromethyl)phenyl)-1-(diphenylmethyl)azetidineHCID 22605395—
Reactant3-(4-tert-butylphenyl)-N-(2-propenyl)azetidine-1-carboxamideHCID 22605403—
Product3-(3-(Trifluoromethyl)phenyl)-N-(2-propynyl)azetidine-1-carboxamideHCID 9817218—

Reaction Steps

This product was prepared from compound (38) and propargylamine using the procedure described for compound (12). m.p. 121° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06831078B1
Source datasetuspto-grants-2004_12
ORD IDord-708a03bd05a74f0e9e6a5bd0bf4064be
Source noteuspto-grants-2004_12