HCID 10249252, compound → HCID 60094112, compound

Participants

Reaction Steps

Analogous to the procedures described in Example 2, N-(4-Chlorobenzyl)-2-(chloromethyl)-7-methyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide (Preparation 1) is treated with pyridin-2-yl(pyrrolidin-2-yl)methanol (Preparation 3) to afford the title compound. Physical characteristics. 1H NMR (400 MHz, DMSO-d6) δ 10.62, 8.70, 8.50, 7.78, 7.54, 7.41-7.33, 7.30, 7.24, 5.13, 4.67, 4.55, 4.04, 3.96, 3.73, 3.15-3.10, 2.94-2.86, 2.33-2.27, 1.84-1.77, 1.64-1.46; MS (ESI+) m/z 523 (M+H)+.

Provenance & Evidence