HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 9908400, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 9798048 | HCID 9798048 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9908400 | HCID 9908400 | 26.2% |
Reaction Steps
In the manner of Example 9's Method 1, employing (2-chloro-4-fluorophenyl)-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-methanone (1.7 g), 60% sodium hydride in oil (0.5 g, degreased with hexane), 1,2,4-triazole (0.70 g) and dimethylformamide (50 ml), the title compound (0.51 g) was obtained as an amorphous solid, MS, m/z: 390.3 (M+H)+, 779.3 (2M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06831079B1 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-44539c02a59e4f48828732a967bbabbb |
| Source note | uspto-grants-2004_12 |