HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → HCID 9951921, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 178519422 | HCID 178519422 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9951921 | HCID 9951921 | 63.9% |
Reaction Steps
In the manner of Example 25, employing [4-(1H-pyrazol-3-yl)-phenyl]-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-methanone (1.0 g), 60% sodium hydride in oil (0.27 g), dimethylformamide (25 ml), and ethyl iodide (0.87 g), the title compound (0.69 g) was obtained as a crystalline solid, m.p. 180-183° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06831079B1 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-1c98d1c09ffd425987104b05b3821883 |
| Source note | uspto-grants-2004_12 |