Sodium Hydroxide → HCID 69844354, compound

HRID 2307371Notes

Reaction equation

[Cl:1][C:2]1[CH:11]=[C:10]([CH:12]2[CH:16]=[CH:15][NH:14][N:13]2[CH3:17])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].[OH-].[Na+]>>[Cl:1][C:2]1[CH:11]=[C:10]([CH:12]2[CH:16]=[CH:15][NH:14][N:13]2[CH3:17])[CH:9]=[CH:8][C:3]=1[C:4]([OH:6])=[O:5]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 86758810HCID 86758810, compound

Product 1

HCID 69844354HCID 69844354, compound

Procedure

The title compound was prepared in the same manner as described in Example 70, employing 2-chloro-4-(2-methyl-1H-pyrazol-3yl)-benzoic acid, methyl ester (0.464 g) and 2.5N sodium hydroxide (1.04 ml). 1H NMR (300 MHz), (DMSO-d6) δ: 3.89 (s, 3H), 6.56 (d, 1H), 7.49 (d, 1H), 7.59-7.90 (m, 3H)

Sources & evidence

ORD record: ord-c349fd1dd2fa40b7b050f8c0d4463038
Source dataset: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06831079B1

Reaction notes

Loading…