HCID 12132433, compound → HCID 12132434, compound

Participants

Reaction Steps

A solution of t-butyl (2S)-2-[(2-methyl-3-nitrophenoxy)methyl]pyrrolidine-1-carboxylate (7.63 g, 21.9 mmol) and 10% Pd/C (0.38 g) in ethanol is hydrogenated (50 psi) at room temperature for 4 h and filtered. The filtrate is concentrated in vacuo to afford the title compound as an off-white solid, 6.66 g, mp 110° C., identified by NMR and mass spectral analyses.

Provenance & Evidence