反应详情

温度

60 °C

10 g (0.15 mol) potassium hydroxide were dissolved in a mixture of 200 ml methyl alcohol and 5 ml water. 4.85 g (18.35 mmol) (E)-4butyloxy-3-methoxycinnamic acid methyl ester was added. The reaction mixture was subsequently heated to 60° C. After 2.5 h the mixture was concentrated by evaporation. The residue was dissolved in 100 ml cold water and acidified to pH=1 with 13.5 ml hydrochloric acid 37 wt. %. The product was filtered off, washed with water and dried at 50° C. under vacuum to give 4.24 g (92%) (E)-4-butyloxy-3-methoxycinnamic acid as white crystals.

1. concentrationAfter 2.5 h the mixture was concentrated by evaporation
2. dissolutionThe residue was dissolved in 100 ml cold water
3. filtrationThe product was filtered off
4. washwashed with water
5. customdried at 50° C. under vacuum