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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2307546Generated: October 26, 2026

Ethyl (4-iodophenyl)acetate → Ethyl (3'-hydroxybiphenyl-4-yl)acetate

https://huagongshe.com/reaction/2307546

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl (4-iodophenyl)acetateHCID 14974990—
Reactant(3-(Methoxymethoxy)phenyl)boronic acidHCID 22606941—
ProductEthyl (3'-hydroxybiphenyl-4-yl)acetateHCID 25139319—

Reaction Steps

In a manner similar to that of Example 1(h), by reaction of 543 mg (3.6 mmol) of 3-methoxymethoxyphenylboronic acid with 700 mg (2.4 mmol) of ethyl 4-iodophenylacetate, 630 mg (68%) of the expected ethyl ester are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06831106B1
Source datasetuspto-grants-2004_12
ORD IDord-7f158b0390ca489a88f2fcd39fa54b93
Source noteuspto-grants-2004_12