Potassium Carbonate → Ethyl 6-{3-[3,4-bis(1-phenylmethanoyloxymethyl)-benzyloxy]phenyl}nicotinate

Participants

Reaction Steps

In a manner similar to that of Example 1(i), by reaction of 277 mg (1.1 mmol) of ethyl 6-(3-hydroxyphenyl)nicotinate with 500 mg (1.1 mmol) of 3,4-bis(benzoyloxymethyl)benzyl bromide and 166 mg (1.2 mmol) of potassium carbonate. The desired product is obtained in the form of white crystals (m.p.=118-120° C.; m=500 mg; Y=73%).

Provenance & Evidence