Tetrabutylammonium Fluoride → HCID 69825588, compound

HRID 2307593Notes

Reaction equation

[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:33]=[CH:34][C:35]=1[CH2:36][O:37][Si](C(C)(C)C)(C)C)[CH2:13][O:14][C:15]1[CH:16]=[C:17]([C:21]2[CH:26]=[CH:25][C:24]([CH:27]([OH:31])[CH:28]([CH3:30])[CH3:29])=[CH:23][C:22]=2[CH3:32])[CH:18]=[CH:19][CH:20]=1)(C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>>[OH:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:33]=[CH:34][C:35]=1[CH2:36][OH:37])[CH2:13][O:14][C:15]1[CH:16]=[C:17]([C:21]2[CH:26]=[CH:25][C:24]([CH:27]([OH:31])[CH:28]([CH3:29])[CH3:30])=[CH:23][C:22]=2[CH3:32])[CH:18]=[CH:19][CH:20]=1

Participants

Reactant 2

HCID 2724141Tetrabutylammonium Fluoride

HCID 22606962HCID 22606962, compound

Product 1

HCID 69825588HCID 69825588, compound

Procedure

In a manner similar to that of Example 27(g), by reaction of 1.1 g (1.7 mmol) of 1-{3′-[3,4-bis-(tert-butyldimethylsilanyloxymethyl)benzyloxy]-2-methylbiphenyl-4-yl}-2-methyl-1-propanol with 3.8 mL (3.8 mmol) of 1.0M tetrabutylammonium fluoride, the desired product is obtained in the form of a colourless oil (m=460 mg; Y=65%).

Sources & evidence

ORD record: ord-02cad27544374089b5899755ed074b20
Source dataset: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06831106B1

Reaction notes

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