3-(4-Nitrophenyl)-1h-pyrrolo[3,2-c]pyridin4-amine → 3-(4-Aminophenyl)-1h-pyrrolo[3,2-c]pyridin-4-amine

Participants

Reaction Steps

Platinum oxide (catalytic) was added to a solution of 3-(4-nitrophenyl)-1H-pyrrolo[3,2-c]pyridin4-amine (0.006 g, 0.024 mmol, 1.0 eq) in MeOH (1 mL) and the reaction mixture was stirred at room temperature under a blanket of hydrogen (50 psi) for 1 h. The reaction mixture was filtered through Celite® and the filtrate concentrated in vacuo to afford the product (0.005 g, 100%) as a solid. MS(ESI+) m/z 225 (M+H)+. Calculated: 225.1140, found: 225.1141.

Provenance & Evidence