4-(3,5-Dichlorophenyl)benzaldehyde → HCID 69720696, compound

HRID 2307620Notes

Reaction equation

HRID 2307620 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[CH:13][C:12]([CH:15]=O)=[CH:11][CH:10]=2)[CH:5]=[C:6]([Cl:8])[CH:7]=1.[C@@H:17]1([NH2:27])[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19][CH2:18]1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[CH:13][C:12]([CH2:15][NH:27][C@@H:17]3[C:26]4[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=4)[CH2:20][CH2:19][CH2:18]3)=[CH:11][CH:10]=2)[CH:5]=[C:6]([Cl:8])[CH:7]=1

Participants

3

Reactant 2

HCID 27581544-(3,5-Dichlorophenyl)benzaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69720696HCID 69720696, compound

Procedure

3′,5′-Dichloro[1,1′-biphenyl]-4-carbaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-d83a72dd757f494b984d0888145517dc
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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