4'-Chloro[1,1'-biphenyl]-4-carbaldehyde → HCID 69721352, compound

HRID 2307622Notes

Reaction equation

HRID 2307622 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]=O)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[C@@H:16]1([NH2:26])[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18][CH2:17]1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][NH:26][C@@H:16]3[C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[CH2:19][CH2:18][CH2:17]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 5925704'-Chloro[1,1'-biphenyl]-4-carbaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69721352HCID 69721352, compound

Procedure

4′-Chloro[1,1′-biphenyl]-4-carbaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-3850198510f94bde9d81357a3fb7fdc6
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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