4'-Fluorobiphenyl-4-carbaldehyde → HCID 69721960, compound

HRID 2307623Notes

Reaction equation

HRID 2307623 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]=O)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[C@@H:16]1([NH2:26])[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18][CH2:17]1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][NH:26][C@@H:16]3[C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[CH2:19][CH2:18][CH2:17]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 13925504'-Fluorobiphenyl-4-carbaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69721960HCID 69721960, compound

Procedure

4′-Fluoro[1,1′-biphenyl]-4-carbaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-8215edd5daf84c5d85fe3cc2a54cb208
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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