2-(4-Fluorophenyl)benzaldehyde → HCID 69722012, compound

HRID 2307628Notes

Reaction equation

HRID 2307628 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([CH:14]=O)=[CH:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.[C@@H:16]1([NH2:26])[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18][CH2:17]1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[CH2:14][NH:26][C@@H:16]2[C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH2:19][CH2:18][CH2:17]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 13924752-(4-Fluorophenyl)benzaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69722012HCID 69722012, compound

Procedure

4′-Fluoro[1,1′-biphenyl]-2-carbaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-b71db6ab2ba944e68c25a0f26d8f58cf
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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