3-(3-(Trifluoromethyl)phenoxy)benzaldehyde → HCID 69722160, compound

HRID 2307649Notes

Reaction equation

HRID 2307649 reaction equation
[F:1][C:2]([F:19])([F:18])[C:3]1[CH:4]=[C:5]([CH:15]=[CH:16][CH:17]=1)[O:6][C:7]1[CH:8]=[C:9]([CH:12]=[CH:13][CH:14]=1)[CH:10]=O.[C@@H:20]1([NH2:30])[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH2:23][CH2:22][CH2:21]1>>[C@@H:20]1([NH:30][CH2:10][C:9]2[CH:12]=[CH:13][CH:14]=[C:7]([O:6][C:5]3[CH:15]=[CH:16][CH:17]=[C:3]([C:2]([F:19])([F:18])[F:1])[CH:4]=3)[CH:8]=2)[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH2:23][CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 5227113-(3-(Trifluoromethyl)phenoxy)benzaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69722160HCID 69722160, compound

Procedure

3-[3-(Trifluoromethyl)phenoxy]benzaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-cd86265ddb814edfbed7279b8e05ddd7
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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