1-Aminotetralin, (S)- → HCID 69721606, compound

HRID 2307658Notes

Reaction equation

HRID 2307658 reaction equation
[O:1]=[C:2]1[C:14]2[CH:13]=[C:12]([CH:15]=O)[CH:11]=[CH:10][C:9]=2[C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2.[C@@H:17]1([NH2:27])[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19][CH2:18]1>>[C@@H:17]1([NH:27][CH2:15][C:12]2[CH:11]=[CH:10][C:9]3[C:8]4[C:3](=[CH:4][CH:5]=[CH:6][CH:7]=4)[CH:2]([OH:1])[C:14]=3[CH:13]=2)[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 70580741-Aminotetralin, (S)-HCID 11160079HCID 11160079, compound

Product 1

HCID 69721606HCID 69721606, compound

Procedure

The product from Example 46B and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 45C to provide the title compound.

Sources & evidence

ORD record
ord-e6feabecb82f4bc4aa6f89735c682f38
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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