3,5-Bis(trifluoromethyl)benzaldehyde → HCID 86586454, compound

HRID 2307674Notes

Reaction equation

HRID 2307674 reaction equation
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:10]=1)[CH:6]=O.[C@@H:17]1([NH2:27])[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19][CH2:18]1>>[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:10]=1)[CH2:6][NH:27][C@@H:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 1362473,5-Bis(trifluoromethyl)benzaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 86586454HCID 86586454, compound

Procedure

3,5-bis(Trifluoromethyl)benzaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-e2f08d2efcc94cc989ece52d458d8e34
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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