3,5-Difluorobenzaldehyde → HCID 69722581, compound

HRID 2307676Notes

Reaction equation

HRID 2307676 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([F:10])[CH:9]=1)[CH:5]=O.[C@@H:11]1([NH2:21])[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH2:13][CH2:12]1>>[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([F:10])[CH:9]=1)[CH2:5][NH:21][C@@H:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 5881603,5-DifluorobenzaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69722581HCID 69722581, compound

Procedure

3,5-Difluorobenzaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-6971b800f52a4675b8057d5dcff02e24
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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