4-Fluoro-3-(trifluoromethyl)benzaldehyde → HCID 69722539, compound

HRID 2307677Notes

Reaction equation

HRID 2307677 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].[C@@H:14]1([NH2:24])[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH2:17][CH2:16][CH2:15]1>>[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH:24][C@@H:14]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:17][CH2:16][CH2:15]2)=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11]

Participants

3

Reactant 2

HCID 5222694-Fluoro-3-(trifluoromethyl)benzaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69722539HCID 69722539, compound

Procedure

4-Fluoro-3-(trifluoromethyl)benzaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-dfe1edb828ab4da9b5e3b600033c6e7a
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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