3-Fluoro-5-(trifluoromethyl)benzaldehyde → HCID 69721941, compound

HRID 2307679Notes

Reaction equation

HRID 2307679 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:9]=1)[CH:5]=O.[C@@H:14]1([NH2:24])[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH2:17][CH2:16][CH2:15]1>>[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:9]=1)[CH2:5][NH:24][C@@H:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 6056863-Fluoro-5-(trifluoromethyl)benzaldehydeHCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69721941HCID 69721941, compound

Procedure

3-Fluoro-5-(trifluoromethyl)benzaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-f2f276a1167543cfb3fed0ebf06a6db1
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

Loading…