3-(TRIFLUOROMETHYLTHIO)BENZALDEHYDE → HCID 69722505, compound
Reaction equation
[F:1][C:2]([S:5][C:6]1[CH:7]=[C:8]([CH:11]=[CH:12][CH:13]=1)[CH:9]=O)([F:4])[F:3].[C@@H:14]1([NH2:24])[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH2:17][CH2:16][CH2:15]1>>[C@@H:14]1([NH:24][CH2:9][C:8]2[CH:11]=[CH:12][CH:13]=[C:6]([S:5][C:2]([F:4])([F:3])[F:1])[CH:7]=2)[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH2:17][CH2:16][CH2:15]1Participants
3
Procedure
3-[(Trifluoromethyl)sulfanyl]benzaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.
Sources & evidence
- ORD record
- ord-242226cb7b714019a11e74a72533b321
- Source dataset
- uspto-grants-2004_12
- Patent number
- US06831193B2
Reaction notes
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