1-Aminotetralin, (S)- → HCID 69722560, compound

HRID 2307685Notes

Reaction equation

HRID 2307685 reaction equation
[C:1]1([S:7][C:8]2[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=2)[CH:11]=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C@@H:16]1([NH2:26])[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18][CH2:17]1>>[C:1]1([S:7][C:8]2[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=2)[CH2:11][NH:26][C@@H:16]2[C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH2:19][CH2:18][CH2:17]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 70580741-Aminotetralin, (S)-HCID 22607995HCID 22607995, compound

Product 1

HCID 69722560HCID 69722560, compound

Procedure

The product from Example 71A and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound as a clear oil. (1.06 g, 46%).

Sources & evidence

ORD record
ord-6d230b9d28574b5484e7006a66bf5333
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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