1-Aminotetralin, (S)- → HCID 69722107, compound

HRID 2307686Notes

Reaction equation

HRID 2307686 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9][C:10]2[CH:11]=[C:12]([CH:15]=[CH:16][CH:17]=2)[CH:13]=O)=[CH:5][CH:4]=1.[C@@H:18]1([NH2:28])[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH2:21][CH2:20][CH2:19]1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9][C:10]2[CH:11]=[C:12]([CH:15]=[CH:16][CH:17]=2)[CH2:13][NH:28][C@@H:18]2[C:27]3[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=3)[CH2:21][CH2:20][CH2:19]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 70580741-Aminotetralin, (S)-HCID 12026853HCID 12026853, compound

Product 1

HCID 69722107HCID 69722107, compound

Procedure

The product from Example 72A and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-2c25985eabbf42609146f8a5b5785df3
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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