1-Aminotetralin, (S)- → N-[3-(methylsulfanyl)benzyl]-N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amine

HRID 2307689Notes

Reaction equation

HRID 2307689 reaction equation
[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=O.[C@@H:11]1([NH2:21])[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH2:13][CH2:12]1>>[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][NH:21][C@@H:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 70580741-Aminotetralin, (S)-HCID 127211713-(Methylsulfanyl)benzaldehyde

Product 1

HCID 69721790N-[3-(methylsulfanyl)benzyl]-N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amine

Procedure

The product from Example 74A and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-19c50976abdd40b881af768e70a76366
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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