1-Aminotetralin, (S)- → HCID 69721700, compound

HRID 2307690Notes

Reaction equation

HRID 2307690 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[CH:12]=O)=[CH:4][CH:3]=1.[C@@H:17]1([NH2:27])[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19][CH2:18]1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[CH2:12][NH:27][C@@H:17]2[C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH2:20][CH2:19][CH2:18]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 70580741-Aminotetralin, (S)-HCID 22608153HCID 22608153, compound

Product 1

HCID 69721700HCID 69721700, compound

Procedure

The product from Example 75A and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-e6a3fb30ffde4013b7e3ddaca0699c6f
Source dataset
uspto-grants-2004_12
Patent number
US06831193B2

Reaction notes

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